Is breast and ovarian cancer genetic?

Hisar Intercontinental Hospital Head of Clinical Laboratories Prof. Dr. Dr. Bekir Sami Awake with breast and ovarian cancer the place of the genetic risk factor and the ones that should not neglect the risk factors ...

In our body, the tissues, the smallest unit of cells, the growth and function of the cells, in a program, such as a handbook, leading to the chromosomes found in the cell nucleus called genes are controlled by voicing Professor. Dr. Awake; 'In the DNA molecule, which is the building stone of the genes, the changes we refer to as mutations lead to many metabolic diseases including cancer. The majority of breast cancers occur at an unknown rate.

In addition, up to 10% is caused by mutated abnormal genes that inherit the child from the mother and the child. The most important of these genes are the BRCA (BReast CANCER gene) genes that prevent DNA from growing uncontrolled by ensuring the stability of DNA.

Mutational changes increase the tendency of hereditary breast and ovarian cancers to develop, preventing genes from functioning. In a woman carrying a BRCA1, BRCA2 mutation, breast cancer the risk of getting caught increases from 10% to 70%, the risk of ovarian cancer increases from 1.5% to 15-40%.

BRCA1, BRCA2 gene mutations also pose a risk in the cervix (uterus), uterus, stomach, pancreas, bile duct and large intestine cancer. Analysis of gene mutations can be done in the blood of patients treated with cancer diagnosis.

By taking genetic counseling and testing gene mutations in other family members according to test results, the risk of cancer can be determined. It is disturbing that hereditary orientation of breast cancer is.

However, treatment is usually possible with early diagnosis and early outcome. With the family history of Kishin is important, gene tests are recommended after 18 years of age, not in babies and children '.

In which cases is a mutation test required?

• If the first of your relatives (mother, sister, girl) is breast cancer and one of them has been diagnosed before the age of 50,
• If there are multiple cancers in your two first-degree relatives,
• If you have breast cancer in three or more of your first or second degree relatives (grandmother, still, aunt)
• If you have first and second degree relatives who have both breast and ovarian cancer at home,
• If you have first and second degree relatives who have ovarian cancer regardless of age in your family,
• Cancers such as pancreas, large intestine and thyroid cancers are widespread in your area and you should definitely take mutation tests to learn your risk situation and take the necessary precautions.