Gene literature results on the effect of ethical properties on cancer development, breast cancer showed a greater risk of developing breast and ovarian cancer in women with a change in the BRCA-1 and BRCA-2 genes that predisposed to the predisposition to breast cancer.
Medical Oncology Expert Assoc. Dr. Metin Şeker told AA correspondent that many cancer types have an important place besides environmental factors and nutrition habits as well as genetic factors, and that the share of genetic causes in cancer development is about 3-10%, varying in each cancer.
"Although there are genetic mutations (changes) in many types of cancer, today's genetic tests are done in breast cancer, ovarian cancer and colon cancer," says Sugar, who is also one of the major developments in cancer treatment. said.
International research results
Pointing out that the genes predisposing to breast cancer are mainly called BRCA-1 and BRCA-2 genes, in healthy people, in normal cells, these genes helped to prevent the uncontrolled cell growth by ensuring the stability of the DNA and thus it was tumor-suppressing.
Sugar has pointed out that if a woman is carrying a dangerous mutation in the BRCA-1 or BRCA-2 gene, the risk of developing breast or ovarian cancer throughout her life is greatly increased.
Sugar said that the BRCA genotype, which shows breast cancer tendency, is a very large number of international studies investigating the effect of cancer on cancer development.
" USA According to the article published in the Journal of National Cancer Institute, the official publication of the National Cancer Institute, a woman with two BRCA-1 or BRCA-2 mutations found a breast cancer risk of 60 percent and an ovarian cancer risk of 59. A joint study of John Hopkins University's 10 major researchers investigating the effect of BRCA mutation found that breast cancer risk was 57 percent and ovarian cancer risk was 40 percent among those with BRCA mutations. "
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